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Medicine & Health / Genetics news 1234

8 new human genome projects offer large-scale picture of genetic difference

April 30, 2008 | User rating: 4.7 / 5 after 9 vote(s) | No comments yet

A nationwide consortium led by the University of Washington in Seattle has completed the first sequence-based map of structural variations in the human genome, giving scientists an overall picture of the large-scale differences ...


Why chemo works for some people and not others

September 18, 2008 | User rating: 4.7 / 5 after 6 vote(s) | No comments yet

MIT researchers have shown that cells from different people don't all react the same way when exposed to the same DNA-damaging agent — a finding that could help clinicians predict how patients will respond to chemotherapy.


Scientists pinpoint genetic driver of narcolepsy

September 29, 2008 | User rating: 4.7 / 5 after 6 vote(s) | No comments yet

Scientists in Japan have identified a genetic mutation linked to narcolepsy, a disease that can cause someone to doze off in mid-sentence or behind the wheel of a car, a study released Sunday reports.


'Junk' DNA proves functional

November 04, 2008 | User rating: 4.7 / 5 after 59 vote(s) | User comments: 30

In a paper published in Genome Research on Nov. 4, scientists at the Genome Institute of Singapore (GIS) report that what was previously believed to be "junk" DNA is one of the important ingredients distinguishing ...


Risk genes for multiple sclerosis uncovered

July 29, 2007 | User rating: 4.6 / 5 after 17 vote(s) | No comments yet

A large-scale genomic study has uncovered new genetic variations associated with multiple sclerosis (MS), findings that suggest a possible link between MS and other autoimmune diseases. The study, led by an international ...


Scientists reshape Y chromosome haplogroup tree gaining new insights into human ancestry

April 02, 2008 | User rating: 4.6 / 5 after 25 vote(s) | No comments yet

The Y chromosome retains a remarkable record of human ancestry, since it is passed directly from father to son. In an article published online today in Genome Research scientists have utilized recently described genetic ...


Selection on genes underlying schizophrenia during human evolution

September 05, 2007 | User rating: 4.6 / 5 after 22 vote(s) | No comments yet

Several genes with strong associations to schizophrenia have evolved rapidly due to selection during human evolution, according to new research in the Proceedings of the Royal Society B.


New route for heredity bypasses DNA

January 04, 2008 | User rating: 4.6 / 5 after 51 vote(s) | User comments: 1

A group of scientists in Princeton's Department of Ecology and Evolutionary Biology has uncovered a new biological mechanism that could provide a clearer window into a cell's inner workings.


Study details regulation of vital tumor suppressor gene p53

September 05, 2007 | User rating: 4.6 / 5 after 8 vote(s) | No comments yet

So vital is the p53 tumor suppressor gene in controlling cancer that its dysfunction is linked to more than half of human cancers. At the same time, the gene’s capacity for shutting down cell growth, even causing cells to ...


Team demos safety of RNA therapy

September 26, 2007 | User rating: 4.6 / 5 after 8 vote(s) | No comments yet

Researchers from MIT, Alnylam Pharmaceuticals and other institutions have demonstrated the safety of a promising type of genetic therapy that could lead to treatments for a wide range of diseases such as cancer.


Researchers discover one of the mechanisms that prevents the spread of colon cancer

September 30, 2007 | User rating: 4.6 / 5 after 8 vote(s) | No comments yet

The first step in the development of colon cancer is the formation of benign tumours, called adenomas, in the intestine. Over time, these tumours may progress to produce colon cancer if they undergo a series of mutations ...


Consortium publishes Phase II map of human genetic variation

October 17, 2007 | User rating: 4.6 / 5 after 16 vote(s) | No comments yet

The International HapMap Consortium today published analyses of its second-generation map of human genetic variation, which contains three times more markers than the initial version unveiled in 2005. In two papers in the ...


Complexity of Crohn's disease revealed as 'gene' count tops 30

June 29, 2008 | User rating: 4.6 / 5 after 8 vote(s) | No comments yet

New research has trebled the number of genetic regions known to be implicated in Crohn's disease, a form of inflammatory bowel disease, to over thirty. The research, published today in the journal Nature Genetics, ...


Obesity genes revealed

August 11, 2008 | User rating: 4.6 / 5 after 8 vote(s) | No comments yet

A study of 228 women has revealed genetic variants responsible for body shape. Based on work in the fruit fly Drosophila melanogaster, research published today in the open access journal BMC Genetics identifies natural ...


Many African-Americans have a gene that prolongs life after heart failure

April 20, 2008 | User rating: 4.6 / 5 after 13 vote(s) | User comments: 1

About 40 percent of African-Americans have a genetic variant that can protect them after heart failure and prolong their lives, according to research conducted at Washington University School of Medicine in St. Louis and ...


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