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Medicine & Health / Genetics news 1234

Researchers discover gene signatures for scleroderma

July 16, 2008 | User rating: not shown ( 1 vote(s) ) | No comments yet

Distinct genetic profiles can discern different groups of patients with scleroderma, a vexing autoimmune disease in which the body turns against itself, Dartmouth Medical School researchers report. Their discovery of distinguishing ...


'Smothered' genes combine with mutations to yield poor outcome in cancer patients

July 15, 2008 | User rating: not rated yet | No comments yet

Johns Hopkins Kimmel Cancer Center researchers have identified a set of genes in breast and colon cancers with a deadly combination of traditional mutations and "smothered" gene activity that may result in poor outcomes for ...


Mutant testis cells behind genetic disorder have survival advantage

July 14, 2008 | User rating: 4.3 / 5 after 7 vote(s) | No comments yet

In a cruel irony, testis cells carrying the mutation that causes Apert's syndrome are fitter than normal cells, even though children born from sperm derived from those cells are weakened by fused fingers, toes and skulls, ...


Gene produces hormones that lead to obesity

July 14, 2008 | User rating: not shown ( 2 vote(s) ) | No comments yet

(PhysOrg.com) -- Obesity and common weight gain share a genetic basis. Professor Philippe Froguel, from Imperial College in Great Britain, and his team from the laboratoire Génomique et physiologie moléculaire des maladies ...


Scientists discover key patterns in the packaging of genes

July 11, 2008 | User rating: 4.8 / 5 after 14 vote(s) | User comments: 1

Although every cell of our bodies contains the same genetic instructions, specific genes typically act only in specific cells at particular times. Other genes are "silenced" in a variety of ways. One mode of gene silencing ...


Common mutations linked to common obesity in Europeans

July 07, 2008 | User rating: 4.2 / 5 after 13 vote(s) | No comments yet

Scientists have discovered two common genetic mutations in people of European ancestry, which affect the production of several hormones controlling our appetite. The mutations have a significant effect on ...


Researchers identify new targets for RNAs that regulate genes

July 06, 2008 | User rating: 5 / 5 after 11 vote(s) | User comments: 1

Tiny strands of genetic material called RNA – a chemical cousin of DNA – are emerging as major players in gene regulation, the process inside cells that drives all biology and that scientists seek to control ...


15 human genomes each week

July 02, 2008 | User rating: 4.8 / 5 after 23 vote(s) | User comments: 2

The Wellcome Trust Sanger Institute has sequenced the equivalent of 300 human genomes in just over six months. The Institute has just reached the staggering total of 1,000,000,000,000 letters of genetic code that will be ...


Complexity of Crohn's disease revealed as 'gene' count tops 30

June 29, 2008 | User rating: 4.6 / 5 after 8 vote(s) | No comments yet

New research has trebled the number of genetic regions known to be implicated in Crohn's disease, a form of inflammatory bowel disease, to over thirty. The research, published today in the journal Nature Genetics, ...


Our genome changes over lifetime, Johns Hopkins experts say

June 25, 2008 | User rating: 4.8 / 5 after 32 vote(s) | No comments yet

May explain many 'late-onset' diseases
Researchers at Johns Hopkins have found that epigenetic marks on DNA-chemical marks other than the DNA sequence-do indeed change over a person's lifetime, and that the degree ...


Researchers find key developmental pathway activates lung stem cells

June 17, 2008 | User rating: 4.5 / 5 after 6 vote(s) | User comments: 1

Researchers from the University of Pennsylvania School of Medicine found that the activation of a molecular pathway important in stem cell and developmental biology leads to an increase in lung stem cells. Harnessing this ...


Researchers discover gene linked to adult-onset obesity

June 10, 2008 | User rating: 4.2 / 5 after 6 vote(s) | No comments yet

Researchers at the University of Minnesota have discovered a gene that may provide a clue as to why obesity rates increase with age. The research was published today in the Proceedings of the National Academy of Sciences.


Stem cell discovery sheds light on placenta development

June 09, 2008 | User rating: not shown ( 1 vote(s) ) | No comments yet

Researchers studying embryonic stem cells have explored the first fork in the developmental road, getting a new look at what happens when fertilized eggs differentiate to build either an embryo or a placenta.


Researchers identify gene that regulates glucose levels

June 03, 2008 | User rating: not shown ( 2 vote(s) ) | User comments: 1

In an effort to understand how genes work, a collaborative study which includes the University of Southern California (USC) has identified a gene that regulates glucose levels. The results, which will be published in the ...


Researchers Pinpoint Gene Mutations Responsible for 10 Percent of Schizophrenia

May 30, 2008 | User rating: not shown ( 3 vote(s) ) | No comments yet

Scans of the genome of patients with schizophrenia have revealed rare spontaneous copy number mutations that account for at least 10 percent of the non-familial cases of the disease. Researchers describe specific ...


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